tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
tert-butyl 3-endo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
CAS: 143557-91-9
Molecular Formula: C12H21NO3
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate - Names and Identifiers
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate - Physico-chemical Properties
| Molecular Formula | C12H21NO3 |
| Molar Mass | 227.3 |
| Density | 1.146 |
| Melting Point | 141.5℃ |
| Boling Point | 328℃ |
| Flash Point | 152℃ |
| pKa | 14.79±0.20(Predicted) |
| Storage Condition | 2-8°C |
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN2811 |
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate - Upstream Downstream Industry
| Downstream Products | N-Boc-exo-3-aminotropane |
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate - Introduction
tert-butyl [3.2.1]octane-8-carboxylate is an organic compound. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-chemical formula: C14H23NO3
-Molecular weight: 253.34g/mol
-Appearance: colorless liquid
-Boiling point: About 200-220 ° C
-Density: about 0.989g/cm³
-Polarity: Polarity
Use:
- tert-butyl [3.2.1]octane-8-carboxylate is often used as an intermediate in organic synthesis. It can be used to synthesize a variety of biologically active compounds, such as drugs, pesticides and antibacterial agents.
Method:
tert-butyl [3.2.1]octane-8-carboxylate can be prepared by the following steps:
1. First, tert-butyl octanoate (t-butyl hexanoate) reacts with methyl acrylate (methyl acrylate) under the catalysis of base to form tert-butyl octane-8-carboxylate (t-butyl 8-hexanoate).
2. Then, in the presence of a catalyst, tert-butyl octane-8-carboxylate was added to boron hexafluoride (boron trifluoride) and isopropylamine (isopropylamine) to form [3.2.1]octane.
Safety Information:
- tert-butyl [3.2.1]octane-8-carboxylate is a chemical and should be used and stored correctly and in accordance with relevant safety procedures.
-This compound may be irritating to the eyes, skin and respiratory system and should be used to avoid contact.
-Wear appropriate protective equipment such as safety glasses, gloves and breathing masks during use.
-In case of contact with skin or eyes, rinse immediately with water and seek medical help.
Please note that any chemicals should be used with caution and in accordance with the relevant safety procedures and recommendations for use.
Nature:
-chemical formula: C14H23NO3
-Molecular weight: 253.34g/mol
-Appearance: colorless liquid
-Boiling point: About 200-220 ° C
-Density: about 0.989g/cm³
-Polarity: Polarity
Use:
- tert-butyl [3.2.1]octane-8-carboxylate is often used as an intermediate in organic synthesis. It can be used to synthesize a variety of biologically active compounds, such as drugs, pesticides and antibacterial agents.
Method:
tert-butyl [3.2.1]octane-8-carboxylate can be prepared by the following steps:
1. First, tert-butyl octanoate (t-butyl hexanoate) reacts with methyl acrylate (methyl acrylate) under the catalysis of base to form tert-butyl octane-8-carboxylate (t-butyl 8-hexanoate).
2. Then, in the presence of a catalyst, tert-butyl octane-8-carboxylate was added to boron hexafluoride (boron trifluoride) and isopropylamine (isopropylamine) to form [3.2.1]octane.
Safety Information:
- tert-butyl [3.2.1]octane-8-carboxylate is a chemical and should be used and stored correctly and in accordance with relevant safety procedures.
-This compound may be irritating to the eyes, skin and respiratory system and should be used to avoid contact.
-Wear appropriate protective equipment such as safety glasses, gloves and breathing masks during use.
-In case of contact with skin or eyes, rinse immediately with water and seek medical help.
Please note that any chemicals should be used with caution and in accordance with the relevant safety procedures and recommendations for use.
Last Update：2024-04-09 21:01:54
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Product Name: tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate Visit Supplier Webpage Request for quotationCAS: 143557-91-9
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Product Name: tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate Visit Supplier Webpage Request for quotationCAS: 143557-91-9
Tel: +86-18821248368
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Product Name: tert-butyl 3-endo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate Visit Supplier Webpage Request for quotation
CAS: 143557-91-9
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View History
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
CYCLOPROPYL-(4-METHOXY-PHENYL)-METHANONE
I-PROPYL CHLOROMETHYL CARBONATE
AKOS 94294
溴化1-丙基-3-甲基咪唑
5-(3-THIENYLMETHYLENE)-2-THIOXOIMIDAZOLIDIN-4-ONE
4-[(9-OXOXANTHEN-2-YL)OXY]BUTYRIC ACID
tert-Butyl 3-(2-(2-(2-azidoethoxyl)ethoxy)ethoxy)propanoate
SODIUM BICARBONATE(1-13C)
5-AMINOPYRIMIDINE
CYCLOPROPYL-(4-METHOXY-PHENYL)-METHANONE
I-PROPYL CHLOROMETHYL CARBONATE
AKOS 94294
溴化1-丙基-3-甲基咪唑
5-(3-THIENYLMETHYLENE)-2-THIOXOIMIDAZOLIDIN-4-ONE
4-[(9-OXOXANTHEN-2-YL)OXY]BUTYRIC ACID
tert-Butyl 3-(2-(2-(2-azidoethoxyl)ethoxy)ethoxy)propanoate
SODIUM BICARBONATE(1-13C)
5-AMINOPYRIMIDINE
Downstream Products for tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate